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About Palmetto Metabolic TeleHealth 

Tysha Holmes - Founder

A patient-turned-provider with 25+ years of clinical experience, Tysha built Palmetto Metabolic TeleHealth after years of personal frustration with fad diets and clinics that overpromised and underdelivered. She leads a science-backed, compassionate approach to metabolic care that helps people feel better, not just lighter. 

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Tysha Holmes, PA-C, MPH, MBA in a medical coat at her desk.
South Carolina state outline with palm trees and water.

Palmetto Metabolic TeleHealth:  From Seed to Bloom

A personal story that grew into a mission to serve South Carolina.

PA‑C | MPH/MBA | Healthcare Entrepreneur | Columbia, SC

I’m Tysha Holmes, PA‑C, MPH/MBA — founder of Palmetto Metabolic TeleHealth. I built this practice to address the struggles many of my patients face. I know what it feels like to search for answers, feel unheard, and try to navigate weight, hormones, and metabolic health without clear guidance.​

  • Palmetto Metabolic TeleHealth grew from that personal experience. What started as a seed — a desire to help people feel seen, supported, and empowered — has become a full‑service metabolic and primary care practice serving individuals and families across Columbia, Lexington, and the greater South Carolina community.

  • Today, our mission is simple: Make evidence‑based metabolic care accessible, compassionate, and convenient — no matter where you live or how busy life gets.

  • We combine clinical expertise with a human‑centered approach, offering telehealth, in‑person community outreach, and personalized treatment plans that meet people exactly where they are. Every service we provide is rooted in the belief that health should feel approachable, not overwhelming — and that every patient deserves a provider who listens.

  • Palmetto Metabolic TeleHealth is still blooming, and so are the people we serve.

· Licensed SC providers 
· Evidence‑based protocols
· HIPAA‑secure telehealth
· 25+ years combined clinical experience.

Serving Columbia, Lexington, Summerville, Charleston, Greenville, and Myrtle Beach, SC

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Mission Statement

We are committed to promoting healthier lives through tailored strategies. Our approach is based on effective methods that enhance your wellbeing. By prioritizing personalized care, we strive to empower you on your wellness journey. It is our pleasure to support you, providing accessible and impactful healthcare to help improve your health and well-being.

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